Xiaofeng Liu Selected Research

7-azaindole dimer

12/2021	Development of anti-breast cancer PI3K inhibitors based on 7-azaindole derivatives through scaffold hopping: Design, synthesis and in vitro biological evaluation.
8/2017	Discovery of a Novel Series of 7-Azaindole Scaffold Derivatives as PI3K Inhibitors with Potent Activity.

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Xiaofeng Liu Research Topics

Disease

33	Neoplasms (Cancer) 03/2022 - 08/2007
13	Breast Neoplasms (Breast Cancer) 01/2022 - 07/2016
12	Infections 08/2022 - 01/2018
10	Inflammation (Inflammations) 01/2022 - 01/2010
5	Bacterial Infections (Bacterial Infection) 01/2022 - 01/2018
5	Carcinogenesis 01/2021 - 02/2002
5	Neoplasm Metastasis (Metastasis) 01/2021 - 09/2016
4	Alzheimer Disease (Alzheimer's Disease) 06/2020 - 01/2014
3	Lung Neoplasms (Lung Cancer) 01/2022 - 02/2002
3	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 04/2015
3	Hemorrhage 10/2021 - 07/2009
3	Colorectal Neoplasms (Colorectal Cancer) 04/2021 - 09/2013
3	Lung Diseases (Lung Disease) 01/2020 - 01/2017
3	Autoimmune Diseases (Autoimmune Disease) 01/2018 - 02/2015
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2017 - 07/2011
3	Ischemia 01/2017 - 07/2009
3	Malaria 04/2013 - 01/2012
2	Sepsis (Septicemia) 01/2022 - 01/2020
2	Brucellosis (Malta Fever) 01/2022 - 01/2019
2	Edema (Dropsy) 01/2022 - 01/2016
2	Sexually Transmitted Diseases (Sexually Transmitted Disease) 01/2022 - 02/2015
2	Leukemia 11/2021 - 01/2018
2	Myocardial Infarction 10/2021 - 01/2021
2	Human Influenza (Influenza) 01/2021 - 01/2016
2	Atherosclerosis 01/2021 - 11/2017
2	Pancreatic Neoplasms (Pancreatic Cancer) 08/2020 - 01/2017
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2020 - 01/2019
2	Osteosarcoma (Osteogenic Sarcoma) 12/2018 - 08/2015
2	Stomach Neoplasms (Stomach Cancer) 10/2018 - 01/2017
2	Prostatic Neoplasms (Prostate Cancer) 01/2018 - 01/2018
2	Communicable Diseases (Infectious Diseases) 01/2018 - 01/2017
2	Lymphatic Metastasis 07/2016 - 02/2002
2	Rheumatoid Arthritis 10/2015 - 02/2015
2	Starvation 09/2006 - 06/2004
1	B-Cell Lymphoma (Lymphoma, B Cell) 05/2022
1	Pregnancy Complications 02/2022
1	Pre-Eclampsia (Preeclampsia) 02/2022
1	Female Infertility 01/2022
1	Autoimmune Diseases of the Nervous System 01/2022
1	Viral Encephalitis 01/2022

Drug/Important Bio-Agent (IBA)

13	Pharmaceutical PreparationsIBA 11/2021 - 02/2002
11	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2002
7	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2014
5	EnzymesIBA 01/2022 - 10/2013
5	Biological ProductsIBA 12/2021 - 04/2003
4	Long Noncoding RNAIBA 01/2022 - 04/2020
4	MicroRNAs (MicroRNA)IBA 01/2022 - 11/2017
4	AntibodiesIBA 01/2019 - 08/2007
4	Ferritins (Ferritin)IBA 09/2006 - 04/2003
3	Glucose (Dextrose)FDA LinkGeneric 03/2022 - 01/2013
3	Phosphotransferases (Kinase)IBA 01/2022 - 01/2012
3	CateninsIBA 09/2021 - 08/2015
3	LipopolysaccharidesIBA 01/2020 - 01/2018
3	VaccinesIBA 02/2019 - 12/2018
3	CytokinesIBA 01/2019 - 01/2016
3	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 06/2004
3	IronIBA 01/2005 - 04/2003
2	OccludinIBA 08/2022 - 01/2022
2	Propofol (Diprivan)FDA LinkGeneric 05/2022 - 07/2009
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 05/2022 - 12/2021
2	CholesterolIBA 01/2022 - 01/2021
2	7-azaindole dimerIBA 12/2021 - 08/2017
2	Apolipoproteins E (ApoE)IBA 11/2021 - 06/2017
2	Phosphatidylinositols (Phosphatidylinositol)IBA 11/2021 - 08/2017
2	RNA (Ribonucleic Acid)IBA 01/2021 - 06/2020
2	Cell Surface ReceptorsIBA 01/2021 - 09/2017
2	Estrogen ReceptorsIBA 01/2021 - 02/2017
2	Messenger RNA (mRNA)IBA 11/2020 - 12/2017
2	Immunoglobulin G (IgG)IBA 01/2020 - 08/2007
2	GalactosamineIBA 05/2019 - 01/2018
2	ApolipoproteinsIBA 01/2019 - 05/2018
2	HaptoglobinsIBA 01/2019 - 11/2017
2	OligodeoxyribonucleotidesIBA 12/2018 - 01/2018
2	FluoroquinolonesIBA 02/2018 - 01/2018
2	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2018 - 01/2018
2	Peptides (Polypeptides)IBA 10/2016 - 06/2004
2	PolymersIBA 01/2016 - 07/2009
2	Dihydroorotate DehydrogenaseIBA 10/2015 - 02/2015
2	Oxidants (Oxidizing Agents)IBA 09/2006 - 06/2004
1	HepcidinsIBA 08/2022
1	Serine Proteases (Serine Protease)IBA 08/2022
1	Doxorubicin (Adriamycin)FDA LinkGeneric 05/2022
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 05/2022
1	AntigensIBA 02/2022
1	Aspartic Acid (Aspartate)FDA Link 01/2022
1	Sorafenib (BAY 43-9006)FDA Link 01/2022
1	Argininosuccinate Synthase (Argininosuccinate Synthetase)IBA 01/2022
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2022
1	Type IV Secretion SystemsIBA 01/2022
1	leukocyte esteraseIBA 01/2022
1	Amino Acids FDA Link 01/2022
1	Indoleacetic Acids (Auxin)IBA 01/2022
1	NAD (NADH)IBA 01/2022
1	CurcuminIBA 01/2022

Therapy/Procedure

12	Therapeutics 01/2022 - 07/2011
4	Drug Therapy (Chemotherapy) 01/2020 - 02/2002
2	Ligation 10/2021 - 04/2015
2	Immunotherapy 10/2016 - 02/2016
1	Aftercare (After-Treatment) 06/2022
1	Radiotherapy 01/2022